Resume

CHERI CLONINGER

email: cheri @ chericloninger.com

North Hills, California

PUBLICATIONS

Protor-2 interacts with tristetraprolin to regulate mRNA stability during stress, Cellular Signalling, January 2012, Volume 24, Issue 1, Pages 309-315.

Inhibition of SAPK2/p38 enhances sensitivity to mTORC1 inhibition by blocking IRES-mediated translation initiation in glioblastoma, Molecular Cancer Therapeutics, September 12, 2011, molcanther.0478.2011.

Phosphomimetic Substitution of Heterogeneous Nuclear Ribonucleoprotein A1 at Serine 199 Abolishes AKT-dependent Internal Ribosome Entry Site-transacting Factor (ITAF) Function via Effects on Strand Annealing and Results in Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitor Sensitivity, The Journal of Biological Chemistry, May 6, 2011, 286, 16402-16413.

Phosphomimetic substitution of hnRNP A1 at serine 199 abolishes AKT-dependent ITAF function via effects on strand annealing and results in mTORC1 inhibitor sensitivity, The Journal of Biological Chemistry, March 16, 2011, Manuscript M110.205096.

AP-1 Regulates Cyclin D1 and c-MYC Transcription in an AKT-Dependent Manner in Response to mTOR Inhibition: Role of AIP4/Itch-Mediated JUNB Degradation, Molecular Cancer Research, January 2011, 9; 115.

Control of pH During Plasmid Preparation By Alkaline Lysis of Escherichia Coli, Journal of Analytical Biochemistry, July 15, 2008, Volume 378, Issue 2, Pages 224-225.

A Nonalkaline Method for Isolating Sequencing-Ready Plasmids, Journal of Analytical Biochemistry, June 15, 2008, Volume 377, Issue 2, Pages 218-222.

The Klenow Machine,2008, the first bioinformatics web-based program written in perl which predicts the precise finished DNA product based upon user input sequences and dNTP additions.

RESEARCH POSITIONS

2010-Present: Research Associate I for the Veterans Affairs Research & Development Department
New title through promotion; continuing to research the involvement of the AKT-mTOR pathway in chemotherapy resistant cancer cell strains

2009-2010: Research Associate II for the Veterans Affairs Research & Development Department
New position through promotion; continuing to research the involvement of the AKT-mTOR pathway in chemotherapy resistant cancer cell strains

2008: Laboratory Assistant for the Veterans Affairs Research & Development Department
Research regarding the involvement of the AKT-mTOR pathway in chemotherapy resistant cancer cell strains

2007: Laboratory Assistant for Dr. Stan Metzenberg at California State University, Northridge
Research included working with various strains of E-coli and the effect of pH, different lysis techniques and temperature on plasmid recovery

2006: Quality Assurance & Licensing Coordinator at Aegis Medical Systems, Inc.
Responsibilities included updating and renewing Federal DEA and State licenses for Schedule II drugs, as well as city business licenses. Certificate issued to commemorate completion of training in California for Federal and State Quality Assurance and Regulatory Compliance

2005: Research Assistant at Zymo Research Biotechnology Laboratory
Offered position after completing summer internship, independently carried out experiments including the induction of an autolysis gene into wild type E. coli Bl-21, and the subsequent effects of L-arabinose, varied buffers, freezing and melting time on the efficiency of E. coli autolysis

2005: Intern at Zymo Research Biotechnology Laboratory
Assisted in manufacturing and biotechnology experiments

2004: Independent Laboratory Study with Dr. Stephen Oppenheimer, Cancer Research, CSUN
Studied carbohydrate involvement in cellular interactions in sea urchin gastrulation and the effects of binding capacity of yeast microbeads to cancer cells

EDUCATION

California State University, Northridge, CA
Bachelor of Science in Biotechnology

New York University, New York, NY
Bachelor of Arts, minor in Anthropology

BIOGRAPHY

Thank you for taking the time to find out more about me and the exciting research in which I am privileged to be involved. Currently I am working on the involvement of the AKT-mTOR pathway in chemotherapy resistant cancer strains. My hobbies include insect collecting, microscopic photography, writing, playing the piano and painting. I love working in the field of biotechnology which is challenging, quickly evolving and presents beneficial therapies for health care and quality of life improvements.